The Foot-and-Mouth Disease Carrier State Divergence in Cattle

The Foot-and-Mouth Disease Carrier State Divergence in Cattle

UNLABELLED The pathogenesis of persistent foot-and-mouth disease virus (FMDV) infection was investigated in 46 cattle that were either naive or had been vaccinated using a recombinant, adenovirus-vectored vaccine 2 weeks before challenge. The prevalence of FMDV persistence was similar in both groups (62% in vaccinated cattle, 67% in nonvaccinated cattle), despite vaccinated cattle having been p...

Redefining the “carrier” state for foot-and-mouth disease from the dynamics of virus persistence in endemically affected cattle populations

The foot-and-mouth disease virus (FMDV) "carrier" state was defined by van Bekkum in 1959. It was based on the recovery of infectious virus 28 days or more post infection and has been a useful construct for experimental studies. Using historic data from 1,107 cattle, collected as part of a population based study of endemic FMD in 2000, we developed a mixed effects logistic regression model to p...

Neutralizing Antibody Response in Cattle Following Vaccination against Foot-and-Mouth Disease

Indirect Complement Fixation in Foot and Mouth Disease. II. Screening of Cattle Serums

Indirect Complement Fixation in Foot-and-Mouth Disease